Driving with no brakes: molecular pathophysiology of Kv7 potassium channels.

نویسندگان

  • Maria Virginia Soldovieri
  • Francesco Miceli
  • Maurizio Taglialatela
چکیده

Kv7 potassium channels regulate excitability in neuronal, sensory, and muscular cells. Here, we describe their molecular architecture, physiological roles, and involvement in genetically determined channelopathies highlighting their relevance as targets for pharmacological treatment of several human disorders.

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عنوان ژورنال:
  • Physiology

دوره 26 5  شماره 

صفحات  -

تاریخ انتشار 2011